Healthcare Conference

London, UK--(Marketwire - June 21, 2007) -

                      SKYEPHARMA TO PRESENT AT JEFFERIES
                             HEALTHCARE CONFERENCE

LONDON, UK, 21 June 2007-- SkyePharma PLC (LSE: SKP) announces today that the Company's Chief Executive Officer, Frank Condella, will make a presentation at the Jefferies Healthcare Conference in New York. Mr Condella will deliver his presentation on Wednesday 27 June 2007 at 11.20 a.m. EDT (4.20 p.m. UKT). Investors may access a live webcast of the presentation at www.skyepharma.com under the Investor Relations tab. The presentation will be archived for 3 months.

For further information please contact:

SkyePharma PLC                         Frank Condella     +44 20 7491 1777
                                       Ken Cunningham
                                       Peter Grant

Financial Dynamics (UK Enquiries)      David Yates        +44 20 7831 3113
                                       Deborah Scott

Trout Group (US Enquiries)             Christine Labaree   +1 617 583 1308
                                       Seth Lewis


About SkyePharma PLC

Using its proprietary drug delivery technologies, SkyePharma develops new
formulations of known molecules to provide a clinical advantage and life-cycle
extension. The Company has eleven approved products in the areas of oral,
inhalation and topical delivery that are marketed throughout the world by
leading pharmaceutical companies.

For more information, visit www.skyepharma.com



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