Protherics PLC Notification of Major Interests in Shares London, UK; Brentwood, TN, US: 16 August 2007 - Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces that on 15 August 2007 a notification of interest in the ordinary share capital of the Company was received from AXA Investment Managers UK Limited on behalf of AXA S.A. and its Group companies, in accordance with the Transparency Obligations Directive. Details of their interest are as follows: 1. Reason for the notification (please tick the appropriate box or boxes) An acquisition of voting rights X An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): 2. Full name of person(s) subject to the AXA S.A., 25 Avenue Matignon, 75008 Paris and its notification obligation: group of companies. 3. Full name of shareholder(s) (if different from 2.): 4. Date of the transaction (and date on which 14 August 2007 the threshold is crossed or reached if different): 5. Date on which issuer notified: 15 August 2007 6. Threshold(s) that is/are crossed or reached: 11% 7. Notified details: A: Voting rights attached to shares Class/type of Situation previous to Resulting situation after the triggering transaction shares the Triggering transaction if possible using Number of Number of Number of Number of voting rights % of voting rights the ISIN CODE Shares Voting shares Rights Direct Direct Indirect Direct Indirect 0702920 37,056,294 37,056,294 345,879 345,879 37,110,415 0.10% 10.94% B: Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration date Exercise/ Conversion Number of voting rights % of voting rights instrument Period/ Date that may be acquired if the instrument is exercised/ converted. Total (A+B) Number of voting rights % of voting rights 37,456,294 11.04% 8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable : Name of Company/Fund Number of Shares % of issued share capital AXA UK Investment Co ICVC 1,121,588 0.33061 UK Smaller Companies Fund Indirect Sun Life Pensions Management Ltd 16,250 0.00479 Direct Sun Life Unit Assurance Ltd 53,913 0.01589 FTSE All Share Tracker Direct Sun Life Pensions Management 275,716 0.08127 FTSE All Share Tracker Direct AXA Framlington 672,805 0.19833 SEI UK Equity Indirect AXA Framlington 1,788,953 0.52734 Throgmorton Trust Indirect AXA Framlington 15,013,453 4.42557 UK Select Ops Indirect AXA Framlington 13,753,131 4.05406 Equity Income Indirect AXA Framlington 1,692,599 0.49893 Managed Balanced Indirect AXA Framlington 1,288,953 0.37995 UK Smaller Companies Indirect AXA Framlington 394,259 0.11622 BAE Systems Pensions Fund CIF Trustees Indirect AXA Framlington 176,049 0.05189 BAE Systems 2000 Pensions Fund Indirect Framlington onshore private clients 1,152,375 0.33969 Indirect Framlington onshore private clients 56,250 0.01658 Indirect Total Direct 345,879 0.10196 Total Indirect 37,110,415 10.93916 TOTAL 37,456,294 11.04112 Proxy Voting: 9. Name of the proxy holder: 10. Number of voting rights proxy holder will cease to hold: 11. Date on which proxy holder will cease to hold voting rights: 12. Additional information: | Ends | For further information please contact: Protherics Nick Staples, Director of Corporate Affairs +44 (0) 7919 480510 Julie Vickers, Company Secretary +44 (0)1928 518010 Financial Dynamics - press enquiries London: Ben Atwell, Anna Keeble +44 (0) 20 7831 3113 New York: John Capodanno, Jonathan Birt +1 212 850 5600 Or visit www.protherics.com This information is provided by RNS The company news service from the London Stock Exchange
Protherics PLC announces Notification of Major Interests in Shares
| Source: Protherics PLC
Cheshire, UK--(Marketwire - August 16, 2007) -