Company Announcement no. 30/2007
To: OMX Nordic Exchange Hørsholm, Denmark, November 29, 2007
LifeCycle Pharma Announces New Product Candidate; Initiates Phase I Clinical
Trial for Sirolimus, an Immunosuppressant to Prevent Organ Rejection after
Transplantation and for the Treatment of Certain Autoimmune Diseases
Hørsholm, Denmark, November 29, 2007; LifeCycle Pharma A/S (OMX: LCP) (the
“Company” or “LCP”), an emerging specialty pharmaceutical company, today
announced a new product candidate LCP-Siro. The active ingredient in LCP-Siro is
Sirolimus, an immunosuppressant for the prevention of organ rejection after
transplantation and for the treatment of certain autoimmune diseases. The
Company has also initiated a Phase I clinical trial for LCP-Siro in healthy
volunteers. Data from the Phase I clinical trial is expected in 2008.
The Company believes that by applying the same reformulation methodology as for
LCP-Tacro, the Company's lead immunosuppressive product candidate, it can
achieve a superior product profile with LCP-Siro, including increased
bioavailability and reduced dosing.
Sirolimus is today marketed by Wyeth under the brand name Rapamune®. Rapamune is
sold as an oral solution and tablet and coats the CYPHER coronary stent marketed
by Johnson & Johnson. Rapamune generates annual sales of approximately $400
million.
About LifeCycle Pharma A/S (“LCP”)
LCP is an emerging specialty pharmaceuticals company that, through innovative
technologies, is able to rapidly develop a portfolio of differentiated products
to meet the unique needs of key therapeutic markets and patient populations.
This includes products for immunosuppression, specifically organ
transplantation, and to combat certain cardiovascular diseases. By using its
unique and patented delivery technology, MeltDose®, LCP is able to develop drugs
with enhanced absorption and thereby increased bioavailability. Currently, the
Company has a diversified near- and medium-term pipeline, including a product
ready for US commercialization, five product candidates in clinical trials and
three in preclinical stages of development. LCP is listed on the OMX Nordic
Exchange under the trading symbol (OMX: LCP). For further information, please
visit www.lcpharma.com.
Contact:
Michael Wolff Jensen
EVP and CFO
+45 4074-6244; MWJ@lcpharma.com
Francesca M. DeMartino
Director, Investor Relations & Corporate Communications
(917) 747-4938; FDM@lcpharma.com
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LifeCycle Pharma Announces New Product Candidate; Initiates Phase I Clinical Trial for Sirolimus
| Source: Veloxis Pharmaceuticals A/S