ITASCA, IL--(Marketwire - February 25, 2008) - First Midwest Bancorp, Inc. ("First Midwest") (NASDAQ: FMBI) today announced that it will be participating in the KBW 2008 Regional Bank Conference to be held in Boston, Massachusetts on February 27th and 28th, 2008. Michael L. Scudder, First Midwest's President and Chief Operating Officer, and Paul F. Clemens, First Midwest's Executive Vice President and Chief Financial Officer, are scheduled to present at the Conference on Thursday, February 28th at 1:00 PM (ET). Interested individuals may access the live, listen-only webcast of the presentation and view a copy of the presentation slides through the Investor Relations section of First Midwest's website at

For those unable to attend the live broadcast, a replay will be available on the aforementioned website for 7 calendar days following the presentation.

First Midwest is the premier relationship-based banking franchise in the growing Chicagoland banking market. As one of the Chicago metropolitan area's largest independent bank holding companies, First Midwest provides the full range of both business and retail banking and trust and investment management services through 102 offices located in 63 communities, primarily in metropolitan Chicago. First Midwest was recently recognized by the Alfred P. Sloan Awards for Business Excellence in Workforce Flexibility in the greater Chicago Area.

Contact Information: CONTACT: Andrea L. Stangl Assistant Corporate Secretary (630) 875-7463 First Midwest Bancorp One Pierce Place, Suite 1500 Itasca, Illinois 60143-9768 (630) 875-7450