London, UK--(Marketwire - March 18, 2008) - NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL RESPONSIBILITY OR CONNECTED PERSONS

This form is intended for use by an issuer to make a RIS notification required by DR 3.1.4R(1).

(1) An issuer making a notification in respect of a transaction relating 
    to the shares or debentures of the issuer should complete boxes 1 to 
    16, 23 and 24.

(2) An issuer making a notification in respect of a derivative relating 
    the shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 
    16, 23 and 24.

(3) An issuer making a notification in respect of options granted to a 
    director/person discharging managerial responsibilities should 
    complete boxes 1 to 3 and 17 to 24.

(4) An issuer making a notification in respect of a financial instrument 
    relating to the shares of the issuer (other than a debenture) should 
    complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.

Please complete all relevant boxes should in block capital letters.

1. Name of the issuer

Smith & Nephew plc

2. State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or

(ii) DR 3.1.4(R )(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or

(iii) both (i) and (ii)

(i) a transaction notified in accordance with DR 3.1.4R(1)(a)

3. Name of person discharging managerial responsibilities/director

Gordon Howe

4. State whether notification relates to a person connected with a person discharging managerial responsibilities/director named in 3 and identify the connected person

N/A

5. Indicate whether the notification is in respect of a holding of the person referred to in 3 or 4 above or in respect of a non-beneficial interest

Gordon Howe

6. Description of shares (including class), debentures or derivatives or financial instruments relating to shares

American Depositary Shares

7. Name of registered shareholders(s) and, if more than one, the number of shares held by each of them

RBC CEES Nominees Limited, as nominee for Abacus Corporate Trustee Limited

8 State the nature of the transaction

Acquisition of ADSs

9. Number of shares, debentures or financial instruments relating to shares acquired

315

10. Percentage of issued class acquired (treasury shares of that class should not be taken into account when calculating percentage)

Less than 0.01%

11. Number of shares, debentures or financial instruments relating to shares disposed

....................................

12. Percentage of issued class disposed (treasury shares of that class should not be taken into account when calculating percentage)

....................................

13. Price per share or value of transaction

60.3 US$ per ADS

14. Date and place of transaction

17 March 2008

15. Total holding following notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage)

315 ordinary shares of US$0.20 each

16. Date issuer informed of transaction

18 March 2008

If a person discharging managerial responsibilities has been granted options by the issuer complete the following boxes

17 Date of grant

17 March 2008 - Grant of Co-investment Plan Awards

18. Period during which or date on which it can be exercised

Co-investment Plan awards - 17 March 2011 - 16 March 2018

19. Total amount paid (if any) for grant of the option

N/A

20. Description of shares or debentures involved (class and number)

938 ADSs - Co-investment Plan

21. Exercise price (if fixed at time of grant) or indication that price is to be fixed at the time of exercise

N/A

22. Total number of shares or debentures over which options held following notification

2,764 in respect of the Co-investment Plan 79,079 in respect of the Share Option plan 15,500 in respect of the Performance Share Plan

23. Any additional information

938 ADS's will vest subject to achievement of performance conditions 1 ADS = 5 ordinary shares of US$

24. Name of contact and telephone number for queries

Gemma Parsons -Assistant Company Secretary - 020 7960 2228

Name and signature of duly authorised officer of issuer responsible for making notification

Gemma Parsons - Assistant Company Secretary

Date of notification

18 March 2008

END

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