Below please find the first part of NeuroSearch's financial statements 2009. The full text can be seen from the enclosed PDF document. -------------------------------------- The Board of Directors of NeuroSearch A/S today considered and adopted the audited Annual Report for the year ended 31 December 2009. The NeuroSearch Group posted an operating loss of DKK 355.8 million in 2009 (2008: DKK 366.0 million), which was on a level with the forecast of a loss in the region of DKK 350 million. NeuroSearch posted a loss after tax of DKK 287.1 million (2008: DKK 382.0 million). In 2009, NeuroSearch passed the most important milestone so far in the company's history, as the first Phase III study, the MermaiHD study, of Huntexil® for the treatment of Huntington's disease was successfully completed. The top line results from the study, available and published in early February 2010, were positive and showed that six months' treatment with Huntexil® leads to a significant improvement of motor symptoms in Huntington patients, and that the drug is very well tolerated and has a very good safety profile. Subsequently, further findings from the study have demonstrated that in addition to a substantial symptomatic effect, Huntexil® also has potential disease modifying properties. NeuroSearch is also evaluating Huntexil® in a clinical Phase IIb study in North America and in a six-month extension phase of the MermaiHD study from which results are expected in the second half of 2010. Based on the results from the MermaiHD study, NeuroSearch has initiated talks with the relevant regulatory authorities about the further process towards market registration of Huntexil® as a new and better therapy for Huntington's disease. With the positive outcome of the MermaiHD study, NeuroSearch has now taken a crucial further step towards its goal of supplying novel innovative and effective drugs for the benefit of patients and of creating a profitable pharmaceutical business. The year 2009 was also a successful year for NeuroSearch in other fields. In June, the FDA approved the Phase III programme for tesofensine for the treatment of obesity and based upon this NeuroSearch is evaluating the development plan and the regulatory strategy for the product. The first Phase III study can be initiated in the course of 2010. In January, an agreement was signed with GSK to increase the number of drug candidates in development under the alliance, and in February and August new drug discovery and development alliances were entered into with Eli Lilly and Janssen respectively. These agreements have generated close to half a billion Danish kroner of guaranteed funding to NeuroSearch. The company's capital base was further strengthened through a successful rights issue in November 2009 with proceeds to the company of more than DKK 400 million. NeuroSearch thus entered 2010 with sound capital resources of almost DKK 1 billion, which are to contribute to ensuring that the development of the company's pipeline can be accelerated. This includes the initiation of Phase III with tesofensine and of Phase II studies with ACR343 and ACR325, both of which are new drug candidates from the same class as Huntexil®, and which are being developed for the treatment of schizophrenia and for dyskinesias in Parkinson's disease. Outlook for 2010 NeuroSearch expects a loss before financials and other shares of results in the region of DKK 400 million in 2010. NeuroSearch expects a continuously high level of activity in the development and commercialisation of Huntexil® and an increased level of activity for other pipeline programmes. The drug discovery activities are expected at the same level as in 2009 and to be related primarily to programmes covered by agreements with external partners. Flemming Pedersen CEO Contacts persons: Flemming Pedersen, CEO, tel: +45 4460 8214 or +45 2148 0118 Hanne Leth Hillman, Vice President, Director of Investor & Capital Market Relations, tel: +45 4460 8212 or +45 4017 5103 Telephone conference: A telephone conference will be held this afternoon at 3 pm Copenhagen time (2 pm London time, 9 am New York time) during which Flemming Pedersen, CEO, Anita Milland, Vice President & CFO and Hanne Leth Hillman, Vice President and Director of Investor & Capital Market Relations, will present the financial statements and answer questions. The telephone conference will be conducted in English and the telephone number is UK: +44 207 509 5139, US: +1 718 354 1226, International: +44 207 509 5139. The related PowerPoint presentation will be available via www.neurosearch.com. About NeuroSearch - Company profile NeuroSearch (NEUR) is a Scandinavian biopharmaceutical company listed on NASDAQ OMX Copenhagen A/S. The core business of the company covers the development of novel pharmaceutical agents, based on a broad and well-established drug discovery platform, focusing on ion channels and central nervous system (CNS) disorders. A substantial share of the activities is partner financed through strategic alliances with Janssen Pharmaceutica, Eli Lilly and Company and GlaxoSmithKline, and licence collaboration with Abbott. The drug pipeline comprises eight clinical (Phase I-III) development programmes: Huntexil® (pridopidine) for Huntington's disease (Phase III), tesofensine for obesity (ready for Phase III), ABT-894 for ADHD (Phase II) in partnership with Abbott, ACR343 for schizophrenia (ready for Phase II), ACR325 to treat dyskinesias in Parkinson's disease (Phase Ib), ABT-560 for the treatment of cognitive dysfunctions (Phase I) in collaboration with Abbott, NSD-788 for anxiety/depression (Phase I) and NSD-721 for social anxiety disorder (Phase I) in partnership with GSK. In addition, NeuroSearch has a broad portfolio of preclinical drug candidates and holds equity interests in several biotech companies.
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