Marina Biotech, Inc. to Report Third Quarter Results on November 10, 2010 at 4:30 p.m. Eastern Time

| Source: Marina Biotech, Inc. Marina Biotech, Inc.

BOTHELL, WA--(Marketwire - November 3, 2010) -  Marina Biotech, Inc. (NASDAQ: MRNA), a leading RNAi-based drug discovery and development company, today announced that it will host a conference call with investors and research analysts on Wednesday, November 10, 2010, at 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time) to provide a business update and discuss financial results for the third quarter ended September 30, 2010.

To participate in the live conference call, U.S. residents should dial 866-770-7125 and international callers should dial 617-213-8066. The participant code for the live conference call is 91213909. To access the 24-hour telephone replay, U.S. residents should dial 888-286-8010 and international callers should dial 617-801-6888. The participant code for the replay is 17851284.

Alternatively, to access the live audio webcast for this conference call, please go to the Event Calendar pages of the Investors section of Marina Biotech's Web Site at http://www.marinabio.com approximately 15 minutes prior to the conference call in order to register, and download any necessary software. A replay of the webcast will be available for 30 days following the event.

About Marina Biotech, Inc.

Marina Biotech (formerly known as MDRNA, Inc.) is a biotechnology company, focused on the development and commercialization of therapeutic products based on RNA interference (RNAi). The Marina Biotech pipeline currently includes a clinical program in Familial Adenomatous Polyposis (a precancerous syndrome) and two preclinical programs -- in hepatocellular carcinoma and bladder cancer. Marina Biotech's goal is to improve human health through the development of RNAi-based compounds and drug delivery technologies that together provide superior therapeutic options for patients. Additional information about Marina Biotech is available at http://www.marinabio.com.

Contact Information:

Contacts:
Marina Biotech, Inc.:
Peter Garcia
Chief Financial Officer
(425) 908-3603