Albany - NY, Aug. 24, 2015 (GLOBE NEWSWIRE) -- According to a new market report published by Transparency Market Research "G-Protein Coupled Receptors (GPCRs) Market (Assay Type: cAMP Assays, Calcium Level Detection Assays, GTPγS Binding Assays, Reporter Gene Assays, Receptor Internalization Assays, and cGMP Assays; Therapeutic Areas: Cardiovascular System, Central Nervous System, Respiratory System, Immune System, Reproductive System, Oncology, and Others): Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2022," the global GPCRs market was valued at USD 1,635.1 million in 2013 and is expected to grow at a CAGR of 8.8% from 2014 to 2022, to reach an estimated value of USD 3,533.4 million in 2022.
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GPCRs represent a large family of cell surface receptors that respond to a diverse range of external stimulus and play a major role in modern pharmacology due to their significant function in cell communication. GPCRs are the target for several drugs discovered and the drugs under development. About 30% of the drugs in the market target GPCRs. Compounds and therapeutics targeting GPCRs have been developed to treat inflammation, pain, neurobiological and several other disorders. Compounds targeting GPCRs are even used in cosmetics and food markets to modulate smell and taste. Key factors driving the growth of the global GPCRs market are rise in demand for various GPCR assays in the ever-increasing drug development activities and high prevalence and growing incidence of cardiovascular, respiratory and reproductive disorders, cancers and nervous system disorders across the world.
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Major GPCR assays include calcium level detection assays, GTPγS binding assays, cAMP assays, reporter gene assays, receptor internalization assays, and cGMP assays. Among these, cAMP assays were the largest segment of the global GPCRs market, accounting for a share of 32.5% in 2013. This segment is projected to expand at the second-highest CAGR during the forecast period. Key factors attributed to the high growth of this segment are increasing demand for cAMP assays in high throughput screening (HTS) and various other major drug discovery platforms, introduction of advanced cAMP assays and wide applicability of these assays in a range of therapeutic applications. In addition, the reporter gene assays segment is also expected to register impressive growth during the forecast period from 2014 to 2022. Factors such as high demand for technologically advanced assays and assay systems, rising demand for highly accurate assays and wide sensitivity, linearity, and large signal-to-background ratio offered by these assays would contribute to the growth of the segment. Increased availability and acceptability of GPCR assays globally would help accelerate the drug discovery processes to develop effective therapeutics for the treatment of the target patient population.
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Based on the therapeutic areas, GPCRs market is segmented into cardiovascular system, central nervous system, respiratory system, immune system, reproductive system and oncology markets. Oncology was the largest segment of the global GPCRs market in terms of revenue and is likely to continue to dominate the market during the forecast period. High prevalence and increasing incidence of several cancers are expected to drive the growth of the segment in the near future. The central nervous system (CNS) segment accounted for the second largest share of the global GPCRs market followed by cardiovascular segment. The other major GPCR therapeutic segments such as respiratory, immune system, reproductive system, and others have been projected to register steady growth during the forecast period from 2014 to 2022.
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Geographically, the GPCRs market has been categorized into four regions: North America, Europe, Asia Pacific, and Rest of the World (RoW). North America accounts for the largest market share for GPCRs primarily due to high awareness about advanced assays, financial capability to purchase expensive equipment and machinery, rising demand for technologically advanced and innovative products in hospitals, and high investment in health care research and development. In addition, the GPCRs market in North America is expected to grow at a high rate due to rise in geriatric population and increase in obesity-related diseases.
Thermo Fisher Scientific, Inc., EMD (Merck) Millipore, Becton, Dickinson and Company, PerkinElmer, Inc., Cisbio Bioassays, Enzo Life Sciences, Inc., DiscoveRx Corporation, Sigma-Aldrich Corporation, Qiagen N.V., Promega Corporation, Abcam plc, and HD Biosciences Co. Ltd. are the major players operating in the global GPCRs market. Among these, Thermo Fisher Scientific, EMD (Merck) Millipore, Becton, Dickinson and Company, PerkinElmer, Inc. and Sigma-Aldrich Corporation operate in most of the segments of GPCRs market. Most of these players continuously innovate, and develop technologically advanced and/or improved GPCR assays and assay systems in order to maintain their position in the global market.
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The global GPCRs market is segmented as follows:
GPCRs Market, by Assay Type
- Calcium Level Detection Assays
- GTPγS Binding Assays
- cGMP Assays
- Reporter Gene Assays
- Receptor Internalization Assay
- cAMP Assays
GPCRs Market, by Therapeutic Area
- Cardiovascular System
- Central Nervous System
- Respiratory System
- Immune System
- Reproductive System
- Oncology
- Others
GPCRs Market, by Geography
North America
- U.S.
- Canada
Europe
- U.K.
- Germany
- France
- Rest of Europe
Asia Pacific
- China
- Japan
- India
- Rest of Asia Pacific
Rest of the World (RoW)
- Latin America
- Middle East
- Africa
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