Source: Helix BioPharma Corp.

Helix BioPharma Corp. Announces Director Resignation

AURORA, ON--(Marketwired - Sep 23, 2015) -

NOT FOR DISTRIBUTION TO UNITED STATES NEWSWIRES OR DISSEMINATION IN THE UNITED STATES

Helix BioPharma Corp. (TSX: HBP) (FRANKFURT: HBP), a biopharmaceutical company developing innovative drug candidates for the prevention and treatment of cancer, today announced that Stacy L. Wills has voluntarily resigned from Helix's board of directors, effective as of September 25, 2015.

Commenting on the resignation, Yvon Bastien, Chairman of the Board, said, "We thank Stace for his hard work and valuable contributions to the board over the past two years. We regret Stace's departure and wish him well in his future endeavours."

About Helix BioPharma Corp.

Helix BioPharma Corp. is a biopharmaceutical company specializing in the field of cancer therapy. The company is actively developing innovative products for the prevention and treatment of cancer based on its proprietary technologies. Helix's product development initiatives include its novel L-DOS47 new drug candidate and its Topical Interferon Alpha-2b. Helix is currently listed on the TSX and FSE under the symbol "HBP".

This press release is not an offer of securities for sale in the United States. Helix's common shares have not been registered under the Securities Act of 1933, as amended, and may not be offered or sold in the United States absent an exemption from registration thereunder.

Contact Information:

Investor Relations:
Maria Lomaka
The Trout Group LLC
Tel: 646 378 2932
mlomaka@troutgroup.com

Helix BioPharma Corp.
3-305 Industrial Parkway South
Aurora, Ontario, Canada, L4G 6X7
Phone: (905) 841-2300
Fax: (905) 841-2244
Web: www.helixbiopharma.com