GUILDFORD, SURREY--(Marketwired - Jul 15, 2016) - New Data From Key Opinion Leaders on Research Undertaken With the Parsortix System Highlights Increasing Use and Broad Potential Applications
ANGLE plc (
Importantly, performance of the system was referenced in two keynote presentations by independent investigators, Caroline Dive of Cancer Research UK Manchester Institute and Klaus Pantel of University Medical Centre Hamburg-Eppendorf (UKE) respectively.
There were three separate scientific poster presentations on Parsortix accepted for presentation at the conference as follows:
1) Fraunhofer ITEM (Institute for Toxicology and Experimental Medicine) Regensburg, Germany: Surface marker independent enrichment of circulating or disseminated cancer cells from blood or lymph nodes using a microfluidic device
2) Cancer Research UK Manchester Institute: Combined circulating tumour cell (CTC) and circulating tumor DNA (ctDNA) analysis of blood from patients with pancreatic cancer
3) ANGLE in-house: A highly sensitive method for circulating tumour cell antigen quantification in liquid biopsy
The published poster presentations will be uploaded to http://www.angleplc.com/the-parsortix-system/download-files/ once available.
The published poster presentations add to the growing published evidence in support of the use of ANGLE's Parsortix system to easily and effectively harvest cancer cells from the blood of patients for analysis.
Key points in the published posters include:
ANGLE Founder and Chief Executive, Andrew Newland, commented:
"These presentations further highlight that Parsortix is extremely flexible and versatile and that its use is building. At EACR, one of the leading European cancer conferences, we have seen customers develop completely novel potential applications for Parsortix; as well as demonstration of use in additional cancer types and the potential for patient drug response to be assessed. In summary, these presentations further highlight the potential market opportunity and key role Parsortix has to play in the fast growing, liquid biopsy space, a rapidly growing market segment for cancer diagnosis and management."
For Frequently Used Terms, please see the Company's website on http://www.angleplc.com/the-parsortix-system/glossary/
This announcement contains inside information.
Notes for editors
About ANGLE plc www.angleplc.com
ANGLE is a specialist medtech company commercialising a disruptive platform technology that can capture cells circulating in blood, such as cancer cells, even when they are as rare in number as one cell in one billion blood cells, and harvest the cells for analysis.
ANGLE's cell separation technology is called the Parsortix™ system and it enables a liquid biopsy (simple blood test) to be used to provide the cells of interest. Parsortix is the subject of granted patents in Europe, the United States, Canada, China and Australia and three extensive families of patents are being progressed worldwide. The system is based on a microfluidic device that captures live cells based on a combination of their size and compressibility. Parsortix has a CE Mark for Europe and FDA authorisation is in process for the United States.
ANGLE has established formal collaborations with world-class cancer centres. These Key Opinion Leaders are working to identify applications with medical utility (clear benefit to patients), and to secure clinical data that demonstrates that utility in patient studies. Details are available here http://www.angleplc.com/the-company/collaborators/
The analysis of the cells that can be harvested from patient blood with ANGLE's Parsortix system has the potential to help deliver personalised cancer care offering profound improvements in clinical and health economic outcomes in the treatment and diagnosis of various forms of cancer.
The global increase in cancer to a 1 in 3 lifetime incidence is set to drive a multi-billion dollar clinical market. The Parsortix system is designed to be compatible with existing major medtech analytical platforms and to act as a companion diagnostic for major pharma in helping to identify patients that will benefit from a particular drug and then monitoring the drug's effectiveness.
As well as cancer, the Parsortix technology has the potential for deployment with several other important cell types in the future.
ANGLE stock trades on the AIM market of the London Stock Exchange under the ticker symbol AGL and in New York on the OTC-QX under the ticker symbol ANPCY. For further information please visit: www.angleplc.com
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Contact Information:
For further information:
ANGLE plc
01483 685830
Andrew Newland, Chief Executive
Ian Griffiths, Finance Director
Cenkos Securities
020 7397 8900
Stephen Keys (Nominated adviser)
Russell Kerr, Oliver Baxendale (Sales)
WG Partners
020 3705 9330
David Wilson
Claes Spang
FTI Consulting
020 3727 1000
001 212 850 5612
Simon Conway, Mo Noonan, Stephanie Cuthbert
Kimberley Ha (US)