Nobilis Therapeutics and Submersible Systems Partner to Create a Portable Inhalation Device for Administration of NBTX-001, a Medical Gas-based Drug Candidate

PORTLAND, OR and HUNTINGTON BEACH, CA--(Marketwired - May 10, 2017) - Nobilis Therapeutics, Inc., a biotechnology company developing inhalation-based therapeutics to treat psychiatric and neurodegenerative disorders, and Submersible Systems, LLC., a leading manufacturer of rescue breathing devices, announced a partnership to create a portable hand-held inhalation device for administration of NBTX-001, a noble gas-based drug candidate. The creation of the first truly portable device will allow patients to receive NBTX-001 safely and independently.

As part of the collaboration, Submersible Systems brings over 30 years of expertise in designing and manufacturing of inhalational rescue devices that have been used by over 250,000 people. Nobilis Therapeutics brings its cutting edge science and intellectual property in the field of inert medical gases, as well as its robust clinical development platform.

"We believe that Submersible Systems is an ideal partner in our quest to develop a miniature device for self-administration of our proprietary drug candidates, beginning with NBTX-001." said Dr. Vlad Bogin, CEO of Nobilis Therapeutics. We were amazed by the ingenuity and simplicity of their solutions, by the quality of their products and immediately felt that merging Submersible's technical and engineering expertise with Nobilis' scientific and clinical competencies would be a winning combination that will allow us to drastically accelerate our development process.

"When Nobilis shared with us their scientific data and development plans, we became very excited," said Christeen Buban, vice-president of marketing at Submersible Systems. They have a highly promising drug candidate, a premier team of medical experts, and are in need of an innovative delivery method that we can definitely help them with. Our commercially available device is already almost made for Nobilis' needs and we are now in the process of its reconfiguration that will transform it into a perfect drug delivery system."

The companies are currently working on customization and testing of drug-device combination and plan to progress on the FDA regulatory pathway as part of their upcoming clinical trials in PTSD, Alzheimer's Dementia and Autism.

About Nobilis Therapeutics, Inc.

Nobilis Therapeutics is a biotechnology company that is focused on development and commercialization of proprietary inhalation-based treatments using controlled device administration of inert gases that have an exceptional safety profile proven by decades of clinical use. The Company has filed multiple patents on the use of inert gases for treatment of a variety of psychiatric and neurodegenerative diseases and leverages the experience of its international team that has successfully used this technology in the treatment of over 500 patients for conditions ranging from panic attacks to substance abuse.

About Submersible Systems, LLC

Submersible Systems has been manufacturing, assembling and supplying innovative life-support breathing devices worldwide to water sport and military markets for over 35 years. Recently acquired by entrepreneur Rick Kearney, the company is dedicated to it's loyal customers and creating new and innovative ways to enhance underwater recreation and quality of life. Being a unique product filling a very specific niche in the marketplace has led the company to work with notable customers such as US and international military agencies, Raytheon, Lockheed Martin, BAE Systems, and notable companies around the globe. The company is ISO certified and proudly makes its products in the USA.