Protein Engineering Market Outlook Report 2025-2030: Applications in Healthcare and Agriculture for Sustainable Practices and Biofortification Present Lucrative Opportunities

The Protein Engineering Market presents opportunities in developing enhanced therapeutic proteins, agricultural innovations, and AI-driven design tools. Growth is driven by technological advancements, government funding, and private investments.


Dublin, May 21, 2025 (GLOBE NEWSWIRE) -- The "Protein Engineering Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2030F" has been added to ResearchAndMarkets.com's offering.

The Protein Engineering Market was valued at USD 2.87 Billion in 2024 and is projected to reach USD 5.74 Billion by 2030, rising at a CAGR of 12.25%.

Technological advancements in molecular biology now allow researchers to synthesize and alter genes encoding specific proteins, facilitating the development of novel and improved biological molecules. As the demand grows for engineered proteins in applications ranging from therapeutic antibodies to agricultural innovations, the market continues to expand rapidly.

Government-backed research funding, growing private investments, and innovation-driven initiatives - such as AI-enabled drug design - are accelerating market development. For instance, Nabla Bio raised USD 11 million in 2021 to build an AI-first platform for next-generation antibody therapeutics, exemplifying the momentum in this sector.

Key Market Driver: Technological Advancements

Cutting-edge technologies have been instrumental in driving the evolution and expansion of protein engineering applications across sectors such as healthcare, agriculture, and industrial biotechnology. CRISPR-Cas9 has revolutionized gene editing by enabling precise, efficient protein modifications. Directed evolution techniques allow researchers to mimic natural selection in the laboratory to optimize protein functions through iterative mutation and screening. High-throughput screening (HTS) systems have improved the speed and scale of protein testing, enabling rapid identification of proteins with desirable traits.

Computational tools, including AI and molecular modeling, now support accurate protein structure predictions and help streamline the design process. Synthetic biology allows for de novo construction of proteins with tailored functionalities, while advances in protein expression systems (yeast, bacterial, and mammalian) have enhanced recombinant protein yields and quality. Collectively, these innovations are facilitating the development of therapeutic proteins, industrial enzymes, and bioengineered agricultural products with unprecedented efficiency.

Key Market Challenge: Complexity of Protein Design

One of the primary challenges in protein engineering is the inherent complexity of protein design. Proteins rely on intricate three-dimensional folding to function correctly, and even minor alterations in amino acid sequences can result in misfolding and loss of activity. Designing proteins that not only fold properly but also exhibit desired properties - such as stability, specificity, and bioactivity - is a highly complex task.

Predicting functional outcomes, ensuring correct protein-ligand or protein-protein interactions, and maintaining stability under physiological conditions remain difficult. Additionally, successful protein design demands multidisciplinary expertise in structural biology, computational modeling, bioinformatics, and chemistry, making collaboration essential. These scientific and technical hurdles limit the pace of development and adoption in certain application areas, especially where precision and reproducibility are critical.

Key Market Trend: Expansion of Protein Engineering in Agriculture

Protein engineering is witnessing a growing footprint in agricultural biotechnology. By modifying plant proteins and enzymes, researchers are enhancing crop traits such as pest resistance, disease tolerance, and resilience to environmental stressors like drought and salinity. Engineered crops can also be enriched with essential nutrients, addressing malnutrition through biofortification. These advances reduce the need for chemical inputs like pesticides and fertilizers, promoting more sustainable and eco-friendly farming practices.

Protein engineering enables the development of genetically modified organisms (GMOs) with targeted improvements, supporting food security and environmental sustainability. The trend toward nutrient-dense and climate-resilient crops underscores the increasing role of protein engineering in transforming agriculture globally.

Key Players Profiled in this Protein Engineering Market Report

  • Agilent Technologies Inc.
  • Amgen Inc.
  • Bruker Corporation
  • Bio-Rad Laboratories Inc.
  • Eli Lilly and Company
  • Merck KGaA
  • Novo Nordisk AS
  • PerkinElmer Inc.
  • Thermo Fisher Scientific Inc.
  • Waters Corporation

Report Scope

In this report, the Global Protein Engineering Market has been segmented into the following categories:

Protein Engineering Market, by Product Type:

  • Insulin
  • Monoclonal Antibodies
  • Coagulation Factors (Blood Factors + Tissue Plasminogen)
  • Vaccines
  • Growth Factors (Hormones + Cytokine)
  • Other Product Types

Protein Engineering Market, by Technology:

  • Irrational Protein Design
  • Rational Protein Design

Protein Engineering Market, by End User:

  • Pharmaceutical and Biotechnology Companies
  • Academic Institutions
  • Contract Research Organizations (CROs)

Protein Engineering Market, by Region:

  • North America
  • Asia-Pacific
  • Europe
  • South America
  • Middle East & Africa

Key Attributes

Report AttributeDetails
No. of Pages189
Forecast Period2024-2030
Estimated Market Value (USD) in 2024$2.87 Billion
Forecasted Market Value (USD) by 2030$5.74 Billion
Compound Annual Growth Rate12.2%
Regions CoveredGlobal

For more information about this report visit https://www.researchandmarkets.com/r/1lvx4d

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