Major Depressive Disorder Pipeline: Insights into Leading Pharma Players, Novel Emerging Therapies, Clinical Trials and Future Outlook | DelveInsight  

Major Depressive Disorder Pipeline is evolving with the novel as well as repurposed therapies in the pipeline along with an improved understanding of mechanisms of action.

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Los Angeles, USA, Aug. 25, 2021 (GLOBE NEWSWIRE) -- Major Depressive Disorder Pipeline: Insights into Leading Pharma Players, Novel Emerging Therapies, Clinical Trials and Future Outlook | DelveInsight  

Major Depressive Disorder Pipeline is evolving with the novel as well as repurposed therapies in the pipeline along with an improved understanding of mechanisms of action.

DelveInsight’s Major Depressive Disorder (MDD) Pipeline Insights report offers exhaustive coverage of the emerging therapy landscape in different stages of development from pre-clinical till a late-end stage, along with dormant, inactive and abandoned therapeutic agents. 

The Major Depressive Disorder Pipeline reports lay down a complete picture of the ongoing clinical trials, partnerships taking place in the domain, recent happenings in space and growth prospects across the Major Depressive Disorder domain.

Some of the key highlights from the Major Depressive Disorder Pipeline report:

  • The Major Depressive Disorder Pipeline report offers a rich analysis of 75+ key players and 75+ key therapies.
  • Major Depressive Disorder pipeline comprises therapies in different stages of the clinical phase such as include Vraylar, PDC-1421, AV-101, AXS-05, Pramipexole, SAGE-217, LY03005, Seltorexant, PH10, PRAX-114, REL-1017, Caplyta, Lumateperone, and others, and several others expected to enter the MDD market in the next decade. 
  • Some of the key companies engaged in strengthening the Major Depressive Disorder Pipeline are Axsome Therapeutics, Luye Pharma, Sage Therapeutics, Chase Therapeutics, Minerva Biosciences, Relmada Therapeutics, Praxis Precision Medicines, Intra-Cellular Therapies, among others
  • In June 2021, Sage Therapeutics and Biogen announced the Phase III results for Zuranolone (WATERFALL Study). The study met its primary endpoint, at Day 15, zuranolone 50 mg showed a statistically significant and clinically meaningful reduction in depressive symptoms as measured by HAMD-17 (p=0.0141) compared to placebo.
  • In June 2021, Small Pharma announced the expansion of its Phase I/IIa clinical trial for its lead product, SPL026, an N,N-dimethyltryptamine ("DMT") based treatment for major depressive disorder.

Request for Sample to know more about the therapies that are set to grab maximum patient pool @ Major Depressive Disorder Emerging Therapies and Forecast 

Major Depressive Disorder (MDD) is one of the most common psychiatric disorders that leads to persistent sadness, loss of interest or pleasure, low energy, worse appetite and sleep, and even suicide, disrupting daily activities and psychosocial functions. It is the leading cause of disease burden in high-income countries. 

For more information on emerging drugs, visit Major Depressive Disorder Pipeline Analysis 

Major Depressive Disorder Pipeline Drugs 

DrugCompanyPhaseMoARoA
VraylarAllergan/Gedeon RichterPhase IIIDopamine D2 receptor partial agonistsOral
PDC-1421Biolite Inc.Phase IINorepinephrine plasma membrane transport protein inhibitorsOral
AV-101 VistaGen TherapeuticsPhase IINMDA receptor modulatorsOral
AXS-05Axsome Therapeutics PreregistrationAdrenergic receptor antagonistsOral
Pramipexole Chase TherapeuticsPhase IIDopamine D2 receptor agonistsOral
SAGE-217Sage TherapeuticsPhase IIIGABA A receptor modulatorsOral
LY03005 Luye Pharma GroupPreregistrationSerotonin uptake inhibitorsOral
Seltorexant Minerva TherapeuticsPhase IIIOrexin receptor type 2 antagonistsOral
PH10 VistaGen TherapeuticsPhase IIChemoreceptor cell stimulantsIntranasal
PRAX-114 Praxis Precision MedicinesPhase II/IIIGABA modulatorsOral
REL-1017 Relmada TherapeuticsPhase IIINMDA receptor antagonistsOral
Caplyta Intra-Cellular TherapiesPhase IIIGlutamate modulatorOral

Request for Sample to know more @ Major Depressive Disorder Pipeline Analysis, Key Companies and Futuristic Trends 

Major Depressive Disorder Therapeutic Assessment 

The Major Depressive Disorder Pipeline report proffers detailed insights into active pipeline assets segmented by Stage, Product Type, Route of Administration, Molecule Type, Target, and Mechanism of Action.

By Product Type

  • Mono
  • Combination

By Stage

  • Discovery 
  • Pre-clinical
  • IND
  • Phase I
  • Phase II
  • Phase III
  • Pre-registration

By Molecule Type 

  • Bispecific Antibody
  • Peptides
  • Small molecule
  • Gene therapy

By Route of Administration

  • Oral
  • Subcutaneous
  • Intranasal
  • Intramuscular

By Mechanism of Action

  • Dopamine D2 receptor agonist
  • Serotonin 1A receptor agonists
  • Glutamate modulator
  • NMDA receptor modulators
  • Adrenergic receptor antagonists
  • GABA A receptor modulators
  • Orexin receptor type 2 antagonists

By Targets

  • Dopamine D2 receptor
  • Serotonin 1A receptor
  • Glutamate
  • NMDA receptor
  • Adrenergic receptor 
  • GABA A receptor
  • Orexin receptor type 2

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Scope of the Report

Coverage: Global
Key Players: Axsome Therapeutics, Luye Pharma, Sage Therapeutics, Chase Therapeutics, Minerva Biosciences, Relmada Therapeutics, Praxis Precision Medicines, Intra-Cellular Therapies, Gedeon Richter, Small Pharma, Clexio Biosciences, VistaGen Therapeutics, among others.

Key Major Depressive Disorder Pipeline Therapies: Vraylar, PDC-1421, AV-101, AXS-05, Pramipexole, SAGE-217, LY03005, Seltorexant, PH10, PRAX-114, REL-1017, Caplyta, Cariprazine, SPL026, CLE-100, among others.

Reach out @ Major Depressive Disorder Pipeline: Novel therapies and Emerging technologies 

Table of Contents 

1Report Introduction
2Major Depressive Disorder Disease Overview
3Major Depressive Disorder Pipeline Outlook
4 Comparative Analysis
5Major Depressive Disorder Therapeutic Products in Clinical Stage
6Major Depressive Disorder Therapeutic Products in Non-clinical Stage
7Major Depressive Disorder Therapeutic Pipeline Analysis
8Inactive Major Depressive Disorder Pipeline Products 
9Appendix
10 Report Methodology
11Consulting Services
12Disclaimer
13About DelveInsight

Visit to know more of what’s covered @ Major Depressive Disorder Emerging Therapies, Treatments and Ongoing Clinical Trials 

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