iTeos gibt klinisch bedeutsame objektive Ansprechrate bekannt – Beobachtung bei jeder Dosis in der Zwischenanalyse des Nachbeobachtungszeitraums der GALAXIES Lung-201-Studie zu Belrestotug + Dostarlimab bei Patienten mit nicht-kleinzelligem Lungenkrebs mit hoher PD-L1-Expression in der Erstlinienbehandlung
September 14, 2024 22:41 ET
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iTeos Therapeutics Inc.
- Klinisch bedeutsame objektive Ansprechrate (Objective Response Rate, ORR) von 63,3–76,7 % bei der Kombination von Belrestotug + Dostarlimab, mit einer bestätigten ORR (confirmed ORR, cORR) von ca....
iTeos annonce un taux de réponse objective cliniquement significatif observé à chaque dose lors de l’analyse intermédiaire de suivi de l’étude GALAXIES Lung-201 portant sur l’association belrestotug + dostarlimab dans le traitement de première ligne des patients atteints d’un cancer du poumon non à petites cellules et présentant un taux de PD-L1 élevé
September 14, 2024 22:41 ET
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iTeos Therapeutics Inc.
- Un taux de réponse objective (TRO) cliniquement significatif de 63,3–76,7 % a été observé avec l’association belrestotug + dostarlimab, avec un TRO confirmé (TROc) d'environ 60 % pour chaque dose. -...
Cullinan Therapeutics Presents Positive Updated Data from Module C of Zipalertinib Pivotal Phase 2b Study at ESMO 2024
September 14, 2024 04:15 ET
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Cullinan Therapeutics, Inc.
Updated data show consistent objective response rate of 40% and manageable safety profile in patients with non-small cell lung cancer harboring epidermal growth factor receptor exon 20 insertion...
Black Diamond Therapeutics Presents Real-World Treatment Practices and Patient Outcomes in Newly Diagnosed NSCLC Patients with Non-Classical Mutations at the European Society for Medical Oncology (ESMO) Congress 2024
September 14, 2024 03:30 ET
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Black Diamond Therapeutics, Inc
Treatment data were analyzed from 3,276 cases of patients with newly diagnosed EGFR mutant NSCLC from Guardant Health Analyses of patients with non-classical EGFR mutations reveal that the majority...
Acrivon Therapeutics Reports Positive Endometrial Cancer Data from Ongoing ACR-368 Registrational Intent Phase 2 Study at ESMO, Advancement of ACR-2316 into Clinic Ahead of Timelines, and Progress on its AP3 Interactome for Proprietary Data Analysis
September 14, 2024 03:10 ET
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Acrivon Therapeutics, Inc
Confirmed overall response rate (ORR) = 62.5% (95% CI, 30.4-86.5) observed in prospectively-selected ACR-368 OncoSignature-positive (BM+) patients with endometrial cancer Achieved statistically...
NuCana Presents Encouraging Data on NUC-7738 in Combination with Pembrolizumab in PD-1 Inhibitor Refractory and Resistant Melanoma Patients at the ESMO Congress 2024
September 14, 2024 03:01 ET
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NuCana plc
BARCELONA, Spain, Sept. 14, 2024 (GLOBE NEWSWIRE) -- NuCana plc (NASDAQ: NCNA) presented final data from the Phase 2 NuTide:701 study at the ESMO Congress on NUC-7738 in combination with...
Immunocore presents Phase 1 data of brenetafusp, an ImmTAC bispecific targeting PRAME, in patients with ovarian cancer
September 14, 2024 03:00 ET
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Immunocore Holdings plc
Immunocore presents Phase 1 data of brenetafusp, an ImmTAC bispecific targeting PRAME, in patients with ovarian cancer Brenetafusp is clinically active as monotherapy and in combination with...
Sutro Biopharma Announces Updated Data from Phase 1b Study of Luvelta in Combination with Bevacizumab at ESMO 2024
September 14, 2024 03:00 ET
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Sutro Biopharma, Inc.
- 4.3 mg/kg of luveltamab tazevibulin (luvelta) in combination with standard dose of bevacizumab (15 mg/kg) every 3 weeks resulted in a 56% objective response rate in patients with late-stage ovarian...
iTeos Announces Clinically Meaningful Objective Response Rate Observed at Every Dose in Follow-up Interim Analysis of GALAXIES Lung-201 Study of Belrestotug + Dostarlimab in First-Line, PD-L1 High Non-Small Cell Lung Cancer Patients
September 14, 2024 02:30 ET
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iTeos Therapeutics Inc.
- Clinically meaningful objective response rate (ORR) of 63.3-76.7% observed with belrestotug + dostarlimab combinations, with confirmed ORR (cORR) at ~60% for every dose- >30% cORR difference...
IO Biotech Announces Positive Results from Phase 2 Trial of IO102-IO103 in the First-line Treatment of Advanced Head and Neck Cancer
September 14, 2024 02:30 ET
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IO Biotech
-- Study Meets Overall Response Rate Primary Endpoint, Encouraging Secondary Endpoint Progression-Free Survival Data in Squamous Cell Carcinoma of the Head and Neck Cohort -- -- No New Safety Signals...